When the ruler of the fourth house is in the twelfth house, this means that you may have come from an occult bloodline. Your parents or past generations may have been involved in some sort of magic, or were members of secret societies.
Alternatively, this placement means that your family house has many secrets. The parents themselves may be secretive persons. This placement can also mean that there was much sickness in your family house, or involvement in illegal matters.
You or your parents may also be involved in dealing with large animals or have an affinity with them, such as horses or elephants.
The ruler of the fourth house in the twelfth house may show that one or both of your parents may have worked in a secluded institution, such as a hospital, prison, monastery, or an ashram.
It could mean that one or both of your parents were separated from the society, such as serving a sentence, or staying a long time in the hospital, or secluding themselves from the society for deep study or spiritual evolution.
Since you are from the same root, you, too, may be a secretive person who will have to spend some time in a secluded institution for work or for some other reason.
This placement also gives a feeling of limitation. You may actually not be more limited than other people, but you will feel limitations more acutely. Also, you will need to take care of your health, trying to prevent manifesting diseases, so that there won’t be any chronic ailments separating you from the society for longer periods of time.
The secretiveness that this placement shows could be because of you being involved in the activities you’d rather keep private. You may also find that you sometimes need to run away from the busyness of the world and stay alone to recharge, and to understand yourself.
Staying alone gives you stability, but if this placement is afflicted, it can also give anxiety and depression. Then it would show the people who cannot but stay on their own, yet that makes them feel lonely and unhappy.
The negative interpretation of this placement is that it can show dishonesty both in your parents or yourself. You may also be dishonest with yourself. It could be difficult to see reality for what it is, and you can convince yourself of something that isn’t true, and convince others of it.
Also, it can give escapist tendencies, when life gets hard. It gives rich imagination and connects you very much to your past life. You may find it easier to remember the bits from your past lives than other people.
Like your parents or past generations, you, too, are likely to be attracted to the participation in secret societies. With age, you may become more and more secluded from the world.
The ruler of the fourth house in the twelfth house may show that your house (childhood or your own) can be in a secluded location. It may be old. If the combination is afflicted, it can show that living in a family house or your own house causes you to get sick, such as because of negative energy there, mold, and so forth.
Inheritances may come with problems. And the same applies to purchasing houses or lands – there could be opposition, delays, unexpected obstacles, and losses. Too much focus on inheritances, lands or real estate can be the source of your undoing, especially if they are tied with your family or the place of your birth.
If this combination is afflicted, you are very much advised to live far from your place of birth, ideally changing the country, and even moving to another continent. You may have a happier life if you rent an apartment abroad, than live in your own home in your home country.
If this combination is afflicted, it would also mean that it’s best for you to stay away from the parent(s) that causes trouble in your life, and avoid being involved in any illegal activity, as you may be caught and imprisoned.
Also, this afflicted combination would mean that you should not approach large animals, though you may have an affinity with them.